• Temperature range — ORSHA110 runs RT+5 °C to 65 °C; ORSHA110R is refrigerated from 4 °C; ORSHA80 offers heating and cooling.
• Capacity — large platforms, and stacked layers on some models — several litres of culture in a single run.
• Speed and orbit — a wide orbit at moderate speed keeps large flasks aerated without splashing the necks.
• Floor space — these are stand-alone cabinets: check door swing, levelling and mains rating before the delivery date.
• Refrigeration — a compressor unit needs clearance for airflow and produces heat and noise — plan where it stands.

A refrigerated model earns its price in two situations: a protocol that runs below ambient, and a warm room where a heating-only chamber cannot hold 30 °C reliably in summer. ORSHA110R covers 4–60 °C and handles both. If every run sits at 30–37 °C in a climate-controlled room, ORSHA110 does the same job for less.