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LACEVAC4 Vacuum Centrifugal Concentrator, Set Vacuum 0.1–100 mbar, Without or With Pump


COLO.Science · Vacuum Centrifugal Concentrator

set vacuum 0.1–100 mbar · RT+5–100 °C · 800–2000 rpm · without pump · with vacuum pump · 30 programs

COLO.Science · Concentration & Evaporation · Vacuum centrifugal concentrators

LACEVAC4 vacuum centrifugal concentrator — set vacuum 0.1 to 100 mbar, without pump or with vacuum pump

The LACEVAC4 vacuum centrifugal concentrator is the model of the line for demanding methods: the vacuum is not only switched on, it is set to a value between 0.1 and 100 mbar and held there automatically. It removes solvent from many small samples at once: vacuum lowers the boiling point, heat from RT+5 °C to 100 °C drives the evaporation, and rotation at 800 to 2000 rpm keeps the liquid at the bottom of the tube. It is offered in two versions — without a pump, for laboratories that already have one, or with a vacuum pump. The rotor for 90 × 1.5 mL tubes is included. Product code PRO5861.

Vacuum, heat and rotation — with the vacuum under control

Small volumes are easy to lose: under vacuum they bump, splash into the neighbouring tube, or dry onto the wall. In the LACEVAC4 vacuum centrifugal concentrator centrifugal force holds every sample down while it boils, so the dry residue collects at the bottom of its own tube, ready to be dissolved again. Because the vacuum is set as a number, a method runs the same way every time.

LACEVAC4 vacuum centrifugal concentrator with LCD panel for time, temperature and vacuum

Key characteristics

  • Vacuum control: automatic; the value is set between 0.1 and 100 mbar and held.
  • Control: LCD panel with time, temperature and vacuum; start and stop with one button each.
  • Programs: 30 user programs and 4 quick keys.
  • Two steps: two times and two temperatures in one run.
  • Speed: 800 to 2000 rpm, adjustable; 530 × g.
  • Temperature: RT+5 °C to 100 °C, accuracy ±1 °C; pre-heating of the chamber.
  • End of run: automatic venting and switch-off.
  • Build: stainless steel chamber with PTFE coating, magnetic drive.

Suitable for

  • Proteomics and genomics — concentration of digests, peptides, DNA and RNA.
  • Methods with a defined vacuum — the pressure is set and repeated from run to run.
  • HPLC and SPE — recovery of collected fractions and eluates.
  • Natural products and extracts — tubes, vials and bottles up to 100 mL.
  • Plates — drying of two 96-well microplates in one run.

Why vacuum lowers the temperature you need

A liquid boils when its vapour pressure reaches the pressure around it. At a set vacuum of 10 mbar water boils at about 7 °C instead of 100 °C, so water and volatile solvents evaporate with little heating. The LACEVAC4 vacuum centrifugal concentrator holds the value you set, so the same solvent boils at the same temperature in every run.

Boiling points of water, butan-1-ol, DMF and DMSO at atmospheric pressure and at 10 mbar

The values in the chart are calculated and rounded. The vacuum that is reached depends on the pump: 5 mbar with the pump offered here; lower set values need a stronger pump. Suitability for a specific solvent is confirmed in the quotation.

Two versions, product codes and rotors

The LACEVAC4 vacuum centrifugal concentrator has no built-in pump. Choose the version by what you already have in the laboratory. Quote and order with the COLO product codes.

LACEVAC4 · without pumpCOLO product code: PRO5861
connect a vacuum pump you already have · ask us whether it is suitable
LACEVAC4 · with vacuum pumpCOLO product code: PRO5861 + PRO3633
diaphragm pump VACUU-CDT30 · PTFE heads, oil-free · 30 L/min · 5 mbar
Control panel of the LACEVAC4 vacuum centrifugal concentrator: time, temperature and vacuum

Rotors

Microtubes · included 90 × 1.5 mL or 2 mL
Microtubes, mixed 66 × 1.5 mL + 24 × 5 mL · 54 × 1.5 mL + 48 × 0.6 mL
PCR strips 24 × 8 × 0.2 mL
Round-bottom tubes 72 × 5 mL · 40 × 10 mL
Conical tubes 18 × 15 mL · 8 × 50 mL
Sample vials 64 × 2 mL
Glass vials 16 × 20 mL · 10 × 30 or 40 mL
Flasks and microplates 6 × 100 mL · 2 × 96-well

One rotor for 90 × 1.5 mL tubes is supplied with the instrument. The other rotors are ordered separately; their product codes are stated in the quotation. Two rotors can be stacked. Tubes stay open during the run.

Technical specifications

Operation and vacuum

Speed 800 to 2000 rpm, adjustable
Maximum centrifugal force 530 × g
Temperature setting range RT+5 °C to 100 °C, ±1 °C
Time range 0 to 9999 min; two steps
Programs 30 user programs, 4 quick keys
Vacuum control range 0.1 to 100 mbar, automatic
Vacuum pump external; not built in
Final vacuum, with pump 5 mbar abs., 30 L/min

Build and general data

Chamber stainless steel 304, PTFE-coated
Vacuum display digital, in mbar
Drive magnetic
Rotors 13 types; 90 × 1.5 mL included
Noise ≤ 55 dB(A)
Supply AC 220 V, 50/60 Hz, 1150 W
Dimensions (L × W × H) 481 × 370 × 294 mm
Weight 28.5 kg

How a run works

Rotor and load

Place the rotor on the drive shaft, put the open tubes in symmetrically and close the lid.

Run

Choose a stored program, or set time, temperature and vacuum — time and temperature in one or two steps — and press start. The LACEVAC4 vacuum centrifugal concentrator starts the rotor first and the pump after it, then holds the vacuum at the set value.

End of run

At the end of the time the pump switches off, the chamber is vented and the rotor stops.

Chamber, vacuum path and cold trap

Vapour leaves the heated chamber of the LACEVAC4 vacuum centrifugal concentrator towards the external pump. A cold trap at −50 °C between chamber and pump condenses it first; this protects the pump and speeds up drying, and is recommended with organic solvents.

Vacuum path of the LACEVAC4 vacuum centrifugal concentrator: chamber, cold trap and external vacuum pump

How the cold trap works

Vapour from the chamber enters the trap through the centre tube and meets a wall held at −50 °C, where it freezes. Only gas that does not condense goes on to the pump. The trap therefore protects the pump from solvent, and because vapour is removed all the time, the pressure in the chamber stays low and drying is faster.

How the cold trap of the LACEVAC4 vacuum centrifugal concentrator works: vapour freezes on the cold wall

Switch the trap on first and start the run when it is cold. When ice has built up on the wall, defrost the trap and drain it.

LACEVAC4 vacuum centrifugal concentrator with the optional cold trap
Optional cold trap for the LACEVAC4

The chamber is stainless steel with a PTFE coating, so the instrument resists common organic solvents, and the magnetic drive needs no shaft seal.

Standard delivery

  • LACEVAC4 vacuum centrifugal concentrator.
  • Rotor for 90 × 1.5 mL tubes.
  • Mains cable.
  • Operating manual.
  • Declaration of conformity and warranty documentation.

The vacuum pump, the cold trap and the optional rotors are ordered separately. Tubes and samples are not part of the instrument. The delivered configuration for a specific order is the one confirmed in the COLO.Science quotation.

Compare the LACEVAC vacuum centrifugal concentrators

Four instruments cover the range from the compact unit for 1.5 mL tubes to programmable vacuum for demanding methods. The LACEVAC4 vacuum centrifugal concentrator is the highlighted column.

Model LACEVAC-1C
compact · external pump
LACEVAC4
programmable · external pump
LACEVAC6
all-in-one · built-in pump
LACEVAC7
touch screen · without or with built-in pump
Vacuum pump external; without or with pump external; without or with pump built-in, 33 L/min without pump or built-in, 2 L/min; stronger external pump as option
Vacuum 5 mbar with pump 5 mbar with pump ≤ 13 mbar built-in pump: −80 to −89 kPa in work, −92 kPa final (about 90 mbar);
optional external pump: 5 mbar
Vacuum display / control analogue gauge; on/off digital; set value 0.1 to 100 mbar digital gauge; on/off digital value on the touch screen; on/off
Speed 1800 rpm, fixed 800 to 2000 rpm 800 to 2000 rpm 300 to 2000 rpm
Centrifugal force 380 × g 530 × g 530 × g —
Temperature RT+5 °C to 70 °C RT+5 °C to 100 °C RT+5 °C to 100 °C RT+5 °C to 80 °C
Operation one button, quick temperature keys LCD, two-step time and temperature LCD, two-step time and temperature, 30 programs 7-inch touch screen
Rotor in delivery 66 × 1.5 mL 90 × 1.5 mL 90 × 1.5 mL none; chosen with the order
Largest tube 50 mL 100 mL 50 mL 100 mL
Microplates — 2 × 96-well 2 × 96-well 2 × 96-well
Dimensions (L × W × H) 350 × 280 × 290 mm 481 × 370 × 294 mm 608 × 370 × 348 mm 580 × 360 × 330 mm
Weight 18 kg 28.5 kg 38 kg 44 kg
Best for small laboratories, 1.5 mL tubes, limited space methods that need a set vacuum; high-boiling solvents one instrument on the bench, no separate pump water and volatile solvents, large tubes, plates

Options for every model

Vacuum pump VACUU-CDT30 · PRO3633Diaphragm pump with two PTFE heads, oil-free and maintenance-free. 30 L/min, final vacuum 5 mbar, 140 W, 10 kg. For models without a pump, and as a stronger pump for models with a built-in one.
Cold trap −50 °C, 2 LStands between the concentrator and the pump, freezes the solvent vapour and protects the pump. Recommended with organic solvents.

Knowledge base

Sample concentration and evaporation on COLO.Science — our knowledge base.

Selection guide

  • Pump. Do you have a vacuum pump, or do you need the version with pump?
  • Vacuum. Which value does the method need? Below 5 mbar a stronger pump is required.
  • Tubes. Type and number per run decide the rotors.
  • Cold trap. Recommended with organic solvents; it protects the pump.
  • Place of use. 481 × 370 mm footprint, 28.5 kg, plus room for the pump.
  • No need to set the vacuum? See the comparison above.
  • Open tubes and nitrogen instead? See the SACO nitrogen sample concentrators.

Configuration notice

This page is provided for orientation and product selection. It does not replace the binding specification, the delivered configuration, the validation protocol or the acceptance criteria confirmed in the official COLO.Science quotation, proforma invoice or order confirmation. Confirm the version, the rotors and the mains voltage version of the LACEVAC4 vacuum centrifugal concentrator for the specific order. B2B prices are quoted net, excluding VAT.

Sales and support for international customers

COLO Lab ExpertsPolje ob Sotli 4, SI-3255 Buče, Slovenia
Phone: +386 70 713 437 · Email: sales@colo.si · Web: colo.si
We supply laboratories across Europe directly and through partners. B2B prices are quoted net, excluding VAT.

Which vacuum for your LACEVAC4 vacuum centrifugal concentrator?

Send the solvent, the tube type, the volume and the number of samples per run. COLO.Science will confirm the version, the rotors and the delivery time.

SKU: PRO5861 Category:

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