COLO.SCIENCE / FREEZE DRYERS
Vacuum freeze drying removes water from a frozen sample by sublimation: the ice passes straight to vapour without melting, so the product never sees a liquid phase and never sees process heat. Protein structure, enzyme activity and cell viability survive the drying step. Select a laboratory freeze dryer around what the product sits in during the run, and around how much water the batch has to give up.
CHOOSE YOUR SAMPLE INTERFACE
01
Bulk product, extracts, culture media and open vials spread thin on stainless steel shelves. Shelf spacing is adjustable, so a tall vial and a shallow tray both fit. This configuration gives the largest drying area and the highest vial count per batch.
02
A manual gland presses the stoppers home while the chamber is still evacuated. Dried product is sealed before it can pick up moisture from room air, which matters for hygroscopic material and for anything stored long term. The cost is one shelf level.
03
Eight independent ports, each taking a round-bottom flask with a Ø29/32 ground glass joint. Liquid freezes as a shell against the flask wall and dries without ever being transferred to a tray; a finished flask comes off while the others stay under vacuum.
FEATURED SERIES / LYOPHIL800
Cold trap to −56 °C, ultimate vacuum 5 Pa and 3 kg of water captured per batch — identical across all four models of this laboratory freeze dryer platform. What separates them is the sample interface: plain shelves, a top press for vial stoppering, an eight-port manifold, or both. The external rotary vane vacuum pump ships with every unit, together with its oil, oil filter and hose.
The vessel, not the trap temperature. Every laboratory freeze dryer in this category reaches the same cold trap temperature and the same ultimate vacuum. Decide first whether the product dries in open trays, in vials that must be closed before air returns, or in flasks on a manifold — the rest of the specification follows from that.
Batch size and water load. Water capture is stated per batch, not per hour. A 3 kg batch covers most research and pilot work; a laboratory that regularly exceeds it belongs in a larger capacity class rather than in a longer cycle.
Bench space and the pump. A benchtop unit needs roughly 60 × 50 cm of bench plus floor or shelf space for the vacuum pump beside it. Because the pump and its consumables ship with the instrument, there is no separate procurement before the first run.
Send the product to be dried, the batch size and water content, the vessel you work in and whether stoppering under vacuum is required. We will confirm which laboratory freeze dryer suits the batch, the drying area needed and the approved configuration.
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LYOPHIL800 benchtop freeze dryers, 4 models, cold trap ≤ −56 °C, ultimate vacuum ≤ 5 Pa, water capture 3 kg per batch. Drying area 0.125 m² on four Ø200 mm shelves or 0.08 m² on three Ø180 mm shelves, up to 920 vials. Top press and 8-port manifold optional, external vacuum pump supplied.
