COLO-DT1206 — Dissolution Tester with Manual Sampling for Tablets & Capsules (12 Vessels)
Overview: pharmaceutical dissolution testing (QC) for tablets & capsules
COLO-DT1206 dissolution tester for tablets and capsules is designed for pharmaceutical dissolution testing and drug release profiling in QC laboratories, method development and regulated environments.
The 12-vessel system enables parallel dissolution runs with precise bath temperature control (RT–45°C, ≤±0.2°C) and stable speed regulation (10–300 rpm) for reproducible results and reliable dissolution profiles.
Compliance: engineered to support requirements referenced for USP and ChP, as well as guiding principles for mechanical validation of dissolution apparatus (per technical documentation).
Tablet & capsule dissolution testing: USP paddle and basket methods
- Tablets and capsules: generate dissolution profiles and verify batch-to-batch consistency in pharmaceutical quality control (QC).
- Method flexibility: switch between paddle and basket methods using a shared drive concept; changeover is designed to be fast after initial height setup.
- Repeatable manual sampling: sampling needle + positioning concept helps keep sampling location consistent across manual sampling points.
- Regulated workflows: user permissions and audit-style records are supported via the built-in software model (configuration dependent), important for GMP/QC settings.
Key features: 12 vessels, temperature stability, speed control and repeatability
- 12 vessels / 12 shafts (1000 mL glass vessels) for parallel pharmaceutical dissolution testing.
- Intelligent automatic lifting of the drive head for improved repeatability of height and centering (more stable mechanical conditions).
- High-precision centering and automatic vessel positioning/locking to reduce station-to-station positional variability.
- Speed control: stepper motor for stable rotation (10–300 rpm) aligned with method requirements.
- Temperature control: water bath heating; accuracy ≤ ±0.2°C; concept of a mobile PT100 probe for verification.
- Manual sampling kit: PEEK sampling probes + positioner and holders for consistent manual workflows (practical for routine QC).
COLO.SCIENCE KNOWLEDGE
Tablet dissolution testing: USP/Pharmacopeia methods, mechanics and validation
Build confident dissolution workflows with clear guidance on paddle vs basket methods, bath temperature control, mechanical performance checks and documentation logic for regulated pharmaceutical testing.
Technical data: dimensions, tolerances and working parameters
| Model | COLO-DT1206 Dissolution Tester with manual sampling |
| Dissolution vessels | 12 vessels |
| Levelness | ≤ 0.2° |
| Verticality (rotation shaft) | 90.0° ± 0.5° |
| Verticality (dissolution vessel) | 90.0° ± 0.5° |
| Coaxiality (vessel/shaft) | ≤ 1.0 mm |
| Swing (rotation shaft) | ≤ 0.2 mm |
| Swing (rotation basket) | ≤ 0.5 mm |
| Speed range | 10–300 rpm |
| Heating | Water bath heating |
| Temperature control | Room temperature–45°C (deviation < ±0.2°C) |
| Sampling | Manual sampling |
| Sampling points | 45 |
| Max working time | 9999 h |
| External dimensions (L×W×H) | 570 × 940 × 630 mm |
| Power supply | AC 220 V ± 10%, 50/60 Hz |
| Power | 2 kW |
| Weight | 80 kg |
Software & data integrity: users, audit trail and storage
- User management: multi-level permissions (administrator / supervisor / operator) and user groups (configuration dependent).
- Account capacity: referenced up to 1000 login accounts; software references 1000+ storage methods (per documentation).
- Audit-style tracking: login, operation and experimental records; electronic data is protected (not editable/deletable per documentation).
- Storage & backup: referenced ~25,000 experimental records; real-time backup via USB or server; remote viewing/printing via server login.
- Paperless reports: network printer support; storage on instrument/USB/server.
- Remote upgrades: remote OS/software upgrade support (service / configuration dependent).
Exact features may vary by configuration and market; confirm requirements with the COLO team.
Standard delivery: accessories, sampling probes and IQ/OQ/PQ documents
- COLO-DT1206 Dissolution Tester with manual sampling (1 set)
- Drive head, 12 positions + automatic lifting device
- 8.0″ high-resolution touch screen
- Vessel covers (12 pcs) + water tank
- 1000 mL glass vessels (12 pcs)
- SS 316L shafts (12 pcs) + SS 316L paddle blades (12 pcs)
- Basket set: tops for basket with stirring shaft (12 pcs) + baskets without cover, 40 mesh (12 pcs)
- Mobile temperature sensor (PT100) (1 pc)
- Calibration balls Φ25 mm (12 pcs) + accessory rack
- Software (data integrity oriented)
- Manual sampling unit: PEEK sampling probes (12 pcs) + manual sampling positioner (1) + probe holders (12 pcs) + silicone dust-proof plugs (12 pcs)
- Documents: Installation (including IQ), OQ, PQ, operating manual, inspection report, certification, warranty card
Technical configuration and regulated-use notice
COLO-DT1206 dissolution testers are configured according to confirmed application requirements and the intended regulatory environment.
Final delivered specifications, included components, software functions and qualification documentation (IQ/OQ/PQ) are defined in the official quotation and technical documentation.
Information presented on this website is for general reference and may be subject to change without prior notice.
