COLO.Science · Technical Specification
COLO-DT1206
Manual Sampling Dissolution Tester · 12 Vessels
Pharmaceutical dissolution testing for tablets and capsules (USP 1/2 methods),
stable water-bath temperature control, stepper-driven speed regulation and
mechanical validation-oriented design.
USP
ChP
FDA
mechanical validation
Document type: Technical Specification Sheet
Format: Landscape (Word/Outlook-ready)
Format: Landscape (Word/Outlook-ready)
Instrument
COLO-DT1206 · 12 positions
Address (HQ)
Polje ob Sotli 4
SI-3255, Slovenia
SI-3255, Slovenia
Contact
COLO-DT1206 · Technical Specification
Document ID: COL-TEC-DT1206-EN
Version: Landscape
Version: Landscape
COLO-DT1206 · manual sampling dissolution tester technical specification sheet
USP
ChP
FDA
mechanical validation
— 12 positions, paddle/basket, manual sampling
📋 general & performance specifications
| instrument identity | |
|---|---|
| model | COLO-DT1206 |
| instrument type | Manual sampling dissolution tester (12-vessel) |
| applicable pharmacopoeia | USP <711>, ChP, FDA mechanical calibration guidelines |
| 🧪 vessel & mechanical parameters | |
| dissolution cups quantity | 12 (borosilicate glass, 1000 mL) |
| levelness (whole platform) | ≤ 0.2° |
| verticality of rotation shaft | 90.0° ± 0.5° |
| verticality of dissolution cup | 90.0° ± 0.5° |
| coaxiality (cup / shaft) | ≤ 1.0 mm |
| swing of rotation shaft | ≤ 0.2 mm |
| swing of rotation basket | ≤ 0.5 mm |
| shaft/basket material | SS 316L |
| cup centering repeatability | centrality change after 1000 removals ≤ 0.3 mm |
| vibration degree | no observable vibration (meets USP requirements) |
| ⚙️ drive & rotation | |
| rotational speed range | 10 – 300 rpm (stepper motor control) |
| speed accuracy / stability | ±1 rpm (within full range) |
| drive head lift | intelligent automatic lifting (imported electric column) |
| 🌡️ temperature control (water bath) | |
| control range | from room temperature up to 45°C |
| temperature deviation | < ±0.2°C (at steady state) |
| sensor type | mobile PT100 (hand-held, non-resident) + integrated monitoring |
| heating method | water bath heating (built-in tank) |
| temperature uniformity (12 cups) | within ±0.2°C (validated) |
| 🧴 sampling (manual) | |
| sampling method | manual with fixed-position PEEK probes |
| sampling kit contents | 12 PEEK sampling probes, locator, 12 fixtures, silicone dust plugs |
| maximum sampling points | 45 programmable intervals |
| maximum working time | 9999 hours (continuous or timed) |
| 📐 dimensions & electrical | |
| external dimensions (L × W × H) | 570 mm × 940 mm × 630 mm (landscape footprint) |
| weight | 80 kg (approx.) |
| power supply | AC 220 V ±10%, 50/60 Hz |
| power consumption | 2 kW (max) |
| 🖥️ control & data | |
| display | 8.0 inch high-resolution colour touch screen |
| user levels | 3 predefined (admin, supervisor, operator) + custom roles |
| user accounts capacity | >1000 |
| method storage | >1000 methods |
| data storage capacity | ~25 000 experimental records (internal / USB / server) |
| audit trail | full login, operation, system exception logs – non-editable |
| report management | paperless, network printer, remote print via server |
| remote upgrade | free remote system updates (USB or network) |
⚙️ key mechanical features
| coaxial paddle/basket design | interchangeable baskets & blades, sealing rings, no re-adjustment after initial height |
| automatic centering cups | self-locking, orientation defined, high precision |
| double bearing shaft top | maintains verticality & coaxiality during long runs |
| lifting mechanism | patented electric lift, reproducible head positioning |
| calibration aids | 12 calibration balls (Φ25 mm) included |
📁 documentation & validation
| IQ / OQ / PQ | installation, operational, performance qualification documents included (paper + electronic) |
| operating manual | detailed instructions (EN) |
| inspection report | factory test certificate |
| warranty card | standard 12-month (extendable) |
| certification | CE / mechanical verification statement |
🔬 optional mechanical cert. system
| model | COLO-260DT (non-standard configuration) |
| function | Bluetooth real-time measurement of shaft verticality, swing, bath levelness; 260-DS software |
| compatibility | fits all open dissolution testers, includes fixing clips |
📦 standard configuration (included)
- drive head, 12 positions
- automatic lifting device
- 8.0" touch screen
- 12 × 1000 mL glass vessels
- 12 × SS 316L shafts
- 12 × SS 316L paddle blades
- 12 × basket tops + 40-mesh baskets
- mobile PT100 temperature sensor
- 12 × calibration balls (Φ25 mm)
- accessory rack & 12 vessel covers
- water tank (integrated)
- software (data integrity, 1000+ accounts/methods)
- manual sampling kit: 12 PEEK probes, locator, 12 fixtures, silicone dust plugs
- installation automated (IQ) booklet
- operational qualification (OQ) booklet
- performance qualification (PQ) booklet
- operating manual, inspection report, certification, warranty card
✅ compliance & regulatory
| USP / ChP / FDA | aligned with <711> and mechanical calibration guidelines (per documentation) |
| data integrity | audit trail, role-based access, protected records (configuration dependent) |
| user permission | administrator, supervisor, operator – customizable groups |
| records capacity | ~25 000 entries referenced, non-editable, exportable |
| network integration | enterprise server connectivity, remote print (configuration dependent) |
🧪 typical pharmaceutical applications
| tablet dissolution profiles (IR/ER) |
| capsule & pill quality control |
| generics development |
| stability testing |
| paddle & basket methods (USP 1 & 2) |
🔧 detailed mechanical tolerances
| parameter | value | test condition / note |
|---|---|---|
| verticality of shaft (relative to vessel) | 90.0° ± 0.5° | measured at any point |
| verticality of cup axis | 90.0° ± 0.5° | reference plane |
| coaxiality between cup and shaft | ≤ 1.0 mm | max offset |
| shaft wobble (total indicated runout) | ≤ 0.2 mm | at 300 rpm |
| basket wobble | ≤ 0.5 mm | 40 mesh basket |
| centering drift after 1000 cup exchanges | ≤ 0.3 mm | automatic centering feature |
| temperature probe accuracy | ±0.1°C (PT100 class A) | at 37°C |
🔧 technical support: phone / email / remote / on-site
📦 spare parts: warehouse, key supplier agreements
🛠️ annual maintenance: 1–2 in-depth visits
🖥️ system upgrade: remote updates (as applicable)
📌 Contact & Support
Headquarters address
Polje ob Sotli 4
SI-3255, Slovenia
Service / qualification support: available by quotation.
For GMP-regulated labs: IQ/OQ/PQ documentation and installation support can be provided.
For GMP-regulated labs: IQ/OQ/PQ documentation and installation support can be provided.
Quick contact
Web:
colo.si
Email:
sales@colo.si
WhatsApp / Viber:
+386 70 713 437
WhatsApp link:
wa.me/38670713437
Knowledge hub:
COLO.Science
Manufacturer & configuration notice (important):
COLO-DT1206 and related dissolution systems are manufactured and supplied in configurations aligned with the confirmed application, user requirements and intended regulatory environment. Therefore, the specifications and included components presented in this document are provided for general information and may represent a typical reference configuration.
For procurement and tender purposes, the only valid and binding specification is the official COLO quotation and the accompanying technical specification that is engineering-approved (issued in writing and signed/authorized by COLO). Any deviations, options, documentation scope (IQ/OQ/PQ) and software functions are defined exclusively in that approved quotation package.
COLO-DT1206 and related dissolution systems are manufactured and supplied in configurations aligned with the confirmed application, user requirements and intended regulatory environment. Therefore, the specifications and included components presented in this document are provided for general information and may represent a typical reference configuration.
For procurement and tender purposes, the only valid and binding specification is the official COLO quotation and the accompanying technical specification that is engineering-approved (issued in writing and signed/authorized by COLO). Any deviations, options, documentation scope (IQ/OQ/PQ) and software functions are defined exclusively in that approved quotation package.