COLO-DT806AT — Automatic Sampling Dissolution System, 8 Cups + Automatic Sampler
OVERVIEW
COLO-DT806AT is an automatic sampling dissolution system consisting of an 8-cup dissolution device and an automatic sampler. It is designed to support integrated workflows including automatic dosing, dissolution and sampling, with precise temperature control, precise sampling, automatic liquid replenishment and automatic cleaning.
The platform supports paddle and basket methods with a coaxial mechanical design to maintain stable hydrodynamics and consistent station-to-station performance. The system also includes an automatic lifting platform that helps preserve verticality and coaxiality during long-term operation.
For regulated environments, COLO-DT806AT provides structured user management, audit tracking, and qualification support with IQ/OQ/PQ documentation.
KEY FEATURES
- 8 cups dissolution system with 1000 mL glass vessels for parallel dissolution runs.
- Rotation control 10–300 rpm for method flexibility.
- Water bath heating with temperature control RT–45°C (deviation < ±0.2°C).
- Temperature monitoring: 8-channel monitoring; measurement resolution 0.01°C.
- Automatic sampling workstation: injection pump sampling with 12 sampling channels and up to 39 sampling points.
- Online secondary filtration: two-stage filter; compatible with common 0.45 μm filters for HPLC-ready samples during sampling.
- Automatic center positioning of dissolution cups (automatic orientation/locking) to reduce positional variability.
- Automatic lifting system to support long-term mechanical stability (verticality/coaxiality).
COLO.SCIENCE KNOWLEDGE
Dissolution testing guide: USP/EP methods, mechanics, validation and best practice
Build confident dissolution workflows with clear explanations of paddle vs basket methods, bath temperature control, mechanical performance, validation logic and documentation. COLO.Science is our knowledge hub for regulated pharmaceutical testing.
COMPLIANCE & VALIDATION
COLO-DT806AT is designed for dissolution testing workflows aligned with major pharmacopeial requirements (e.g., USP and ChP) and mechanical validation guiding principles referenced for dissolution meters.
- Standards reference: USP, ChP, Mechanical Validation Guiding Principles (per technical documentation).
- Qualification support: IQ/OQ/PQ documentation and related validation materials can be provided.
- Optional: Precision Mechanical Verification System (COLO-260DT) is referenced as a non-standard configuration.
Full validation documentation set and supporting materials can be provided on request.
MODEL & DIMENSIONS
| Model | Stations | External dimensions (L×W×H) | Weight |
|---|---|---|---|
| COLO-DT806AT (Host) | 8 cups | 570 × 720 × 630 mm | 60 kg |
| Automatic Sampler (Workstation) | 12 channels / 39 points (method dependent) | 640 × 445 × 430 mm | 40 kg |
TECHNICAL SPECIFICATIONS
| Product | COLO-DT806AT Automatic Sampling Dissolution System |
| Stations | 8 cups |
| Levelness | ≤ 0.2° |
| Verticality (rotation shaft) | 90.0° ± 0.5° |
| Verticality (dissolution cup) | 90.0° ± 0.5° |
| Coaxiality (cup/shaft) | ≤ 1.0 mm |
| Swing (rotation shaft) | ≤ 0.2 mm |
| Swing (rotation basket) | ≤ 0.5 mm |
| Speed range | 10–300 rpm |
| Heating | Water bath heating |
| Temperature control | Room temperature–45°C (deviation < ±0.2°C) |
| Temperature monitoring | 8 channels; resolution 0.01°C |
| Sampling method | Injection pump sampling |
| Maximum sampling | 20 mL (sampling accuracy < ±0.1) |
| Minimum sampling interval | First point 2 min; other points 5 min |
| Sampling channels | 12 |
| Sampling points | 39 |
| Filter | Two-stage filter |
| Sampling rack | 104 position test tube rack; 104 liquid phase bottle rack |
| Max working time | 9999 h |
| Power supply | AC 220 V ± 10%, 50/60 Hz |
| Power | Host: 2 kW; Sampler: 0.3 kW |
| Weight | Host: 60 kg; Sampler: 40 kg |
Detailed mechanical validation tolerances and full documentation package are available on request.
SOFTWARE & DATA INTEGRITY
- User management: multi-level permissions (administrator / supervisor / operator) and user groups.
- Account capacity: preset up to 1000 login accounts; software references 1000+ storage methods.
- Audit tracking: login, operation, experimental records and exception reports; electronic data is protected (not editable/deletable per documentation).
- Storage: capacity referenced at ~25,000 experimental data records.
- Backup & access: real-time backup via USB or enterprise server; remote viewing/printing via enterprise server login.
- Paperless reports: network printer support; storage on instrument/USB/server.
- Remote upgrades: remote OS/software upgrade support (configuration dependent).
Exact features may vary by configuration and market; confirm requirements with the COLO team.
STANDARD DELIVERY & OPTIONS
Standard delivery (typical):
- COLO-DT806AT Intelligent Dissolution with Automatic sampling workstation (1 set)
- Drive head (8 positions) + automatic lifting device
- 8.0″ high-resolution touch screen
- Temperature monitoring system + mobile temperature sensor (PT100)
- Water tank + vessel covers (8 pcs)
- 1000 mL glass vessels (8 pcs)
- SS 316L shafts (8 pcs) + SS 316L paddle blades (8 pcs)
- Basket set: tops for basket with stirring shaft (8 pcs) + baskets without cover, 40 mesh (8 pcs)
- Sample delivery trays (8 pcs) + calibration balls Φ25 mm (8 pcs) + accessory rack
- Software (data integrity oriented)
- Automatic sampling workstation: 8-channel syringe pump with secondary online filtering + sample collector (104 positions)
- Rack for HPLC vials (1.5 mL); sampling test tubes / vials (as specified)
- Documents: Installation (including IQ), OQ, PQ, operating manual, inspection report, certification, warranty card
Options / accessories (available on request):
- Precision Mechanical Verification System (COLO-260DT) (non-standard configuration)
- Additional sampling consumables and filtration accessories
- Extended server integration and connectivity modules (configuration dependent)
- On-site qualification support and 3Q verification services (IQ/OQ/PQ)
Technical and GMP configuration notice
COLO-DT806AT dissolution instruments are configured in accordance with confirmed application requirements and intended regulatory environment.
Final delivered specifications, included components, software functions and qualification documentation (IQ/OQ/PQ) are defined in the official quotation and technical documentation.
For GMP-regulated laboratories, installation support and qualification documentation can be provided according to project scope.
Information presented on this website is for general reference and may be subject to change without prior notice.
