COLO.Science — Water Quality / Titrimetric Analysis — TITRO4
TITRO4 automatic potentiometric titrator
TITRO4 automatic potentiometric titrator is a laboratory titration system for
automatic potentiometric titration, pH/mV endpoint detection and routine titrimetric analysis.
It supports DET dynamic equivalence point titration, MET monotone equivalence point titration,
SET preset endpoint titration and MAT manual titration, with LCD-guided operation,
replaceable high-accuracy burette options, GLP-oriented data storage and RS-232 / USB connectivity for reporting and PC control.
| Overview | HTML Spec | RFQ |
COLO.Science — Laboratory Titration / Water Quality Instruments
Automatic potentiometric titrator for endpoint titration, pH/mV measurement and GLP-oriented records
The TITRO4 automatic potentiometric titrator is designed for routine and method-based titrimetric analysis
in laboratories that require controlled dosing, pH/mV endpoint detection, repeatable burette performance and clear
titration result review. It supports acid-base, redox, precipitation and complexometric titration workflows depending
on selected electrodes, reagents and validated laboratory procedure.
TITRO4 combines LCD-guided operation, display of titration methods and curves, replaceable 10 mL or 20 mL burettes,
pH calibration and measurement functions, GLP-compliant data storage, RS-232 communication and full PC control via
USB or RS-232.
Key features
- Automatic potentiometric titrator for pH/mV endpoint-based titrimetric analysis.
- DET, MET, SET and MAT modes for flexible equivalence point, endpoint and manual workflows.
- pH 0.00–14.00 and mV −1800.0 to +1800.0 measurement ranges.
- Repeatability ≤0.2% for routine automated titration applications.
- Replaceable 10 mL / 20 mL burette with high-accuracy dosing options.
- GLP-compliant storage for up to 50 titration data sets and the latest titration curve.
Suitable for
- Acid-base titration, including selected aqueous and non-aqueous methods.
- Redox titration and oxidation-reduction endpoint workflows.
- Precipitation titration, including chloride and related routine QC methods.
- Complexometric titration, including selected EDTA and metal ion determinations.
- Food, environmental, petrochemical, pharmaceutical and industrial quality-control laboratories.
- Education, titration method development and electrode / endpoint demonstration work.
Technical specifications — TITRO4 automatic potentiometric titrator
| Model | TITRO4 / Ti-40 |
| SKU | PRO6103 |
| Product type | Automatic potentiometric titrator / automatic titration system |
| Analysis type | Titrimetric analysis with pH/mV endpoint detection |
| Titration modes | DET, MET, SET and MAT |
| Supported titration methods | Acid-base, redox, precipitation and complexometric workflows |
| Repeatability | ≤0.2% |
| Burette accuracy | 10 mL ±0.025 mL; 20 mL ±0.035 mL |
| Mechanical unit resolution | 1/14000 |
| mV measuring range | −1800.0 to +1800.0 mV |
| mV resolution / accuracy | 0.1 mV · ±0.05% FS |
| pH measuring range | 0.00 to 14.00 pH |
| pH resolution / accuracy | 0.01 pH · ±0.01 pH |
| Fluctuation | ±0.3 mV / 3 h |
| Temperature compensation range | −5.0 to 105.0 °C |
| Temperature resolution / accuracy | 0.1 °C · ±0.3 °C |
| Data storage | 50 titration data sets, GLP compliant; one latest titration curve |
| Communication / control | RS-232 communication; full PC control via USB or RS-232 |
| Power supply | AC adapter 100–240 V input, DC 24 V output |
| Dimensions | 340 × 400 × 400 mm |
| Weight | 10 kg net; 12 kg gross |
| Carton size | 540 × 490 × 480 mm |
Final titration performance depends on electrode selection, reagent quality, burette condition, sample preparation,
titration method settings, calibration routine and laboratory procedure. Delivered configuration should be confirmed
through the official quotation.
Titration modes, guided operation and data handling
DET and MET modes
DET mode supports dynamic equivalence point titration, while MET mode supports monotone equivalence point titration
with defined dosing behavior. These modes are useful for endpoint discovery, method validation and repeatable titration programs.
SET and MAT modes
SET mode stops titration at a preset pH or mV endpoint. MAT mode gives the operator manual control while the instrument
records the pH/mV response, which is practical for training, method development and electrode checks.
GLP-oriented records
TITRO4 stores up to 50 titration data sets and the latest titration curve. RS-232 and USB/RS-232 PC control support
practical reporting, method supervision and laboratory documentation.
Standard delivery and included components
Dosing and titration hardware
- 10 mL burette
- Replaceable high-accuracy burette system
- Mechanical resolution 1/14000
Electrodes and probe
- 232-01 reference electrode
- 213-01 platinum electrode
- 216-01 silver electrode
- 217-01 reference electrode
- 231-01 pH indicator electrode
- T-818-B-6 temperature probe
Calibration standards
- NIST pH standard solution pH 4.01, 50 mL/vial
- NIST pH standard solution pH 7.00, 50 mL/vial
- NIST pH standard solution pH 10.01, 50 mL/vial
COLO.Science video
TITRO4 video presentation is in preparation
The upcoming video can show burette installation, electrode connection, pH calibration, DET/MET/SET/MAT mode selection,
titration curve review, data export and practical operation in routine laboratory conditions.
COLO.Science knowledge
Learn more about water quality and electrochemical analysis
Explore COLO.Science articles about pH measurement, electrodes, buffers, calibration routines and practical workflows
used in water-quality and laboratory electrochemical analysis.
Applications and laboratory value
Water and environmental laboratories
TITRO4 can support alkalinity, acidity, chloride and related titrimetric workflows where pH/mV endpoint detection is required.
Food and beverage QC
Automated endpoint titration can support acidity, salt/chloride and selected redox or complexometric methods, depending on validated procedures.
Pharmaceutical and chemical QC
Repeatable burette dosing, GLP records and PC communication support routine titration programs in controlled laboratory workflows.
Education and method development
Multiple titration modes, curve review and manual mode make TITRO4 useful for teaching titration theory and developing practical methods.
Selecting the right titration configuration
When selecting the TITRO4 automatic potentiometric titrator, the method, electrode set, burette volume,
reagent chemistry, endpoint criterion and sample preparation should be matched to the target application. Acid-base,
precipitation, redox and complexometric titrations may require different electrodes, reagents and accessories.
COLO.Science can support selection of electrodes, burettes, reference solutions, pH buffers, titration accessories and
documentation so the final configuration matches the laboratory method and quotation scope.
TITRO4 automatic potentiometric titrator for routine laboratory titration
The TITRO4 automatic potentiometric titrator is useful when a laboratory needs an automated platform for
pH/mV endpoint titration, repeatable burette dosing and structured titration records. Its DET, MET, SET and MAT modes give
laboratories flexibility for routine methods, method optimization and operator-guided titration work.
In practice, titration quality depends on the titrator, electrode condition, calibration, reagent concentration, sample matrix,
endpoint settings and laboratory SOP. TITRO4 provides the measurement and dosing platform, while COLO.Science can help define
the correct electrodes and accessories for the final application.
Configuration notice
Automatic titrators may be delivered in different configurations depending on selected electrodes, burette volume,
reagents, accessories, PC-control requirements and validated method. The official quotation defines the final delivery scope.
Website content is provided for general product presentation and may not represent the exact delivered configuration.
Specifications may change without notice.




