COLO.SCIENCE – ULTRASONIC HOMOGENIZERS
USP-400 Series: Handheld Ultrasonic Homogenizer – 250W or 400W, 0.1–300 mL, Touch Control (PRO5691 / PRO5692)
The USP-400 series handheld ultrasonic homogenizer uses ultrasonic cavitation for cell disruption, emulsification, dispersion, homogenization, extraction, defoaming, cleaning and nano-material preparation.
The series is available in two configurations: PRO5691 (2.5–250 W, 0.1–150 mL) and PRO5692 (4–400 W, 0.1–300 mL), each supplied with a Φ5 mm standard horn. Both models feature a true‑color capacitive touch display, automatic frequency tracking and real‑time sample temperature detection.
Why users switch to USP-400
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Firstly, true handheld: 1.2 kg – move between laminar flow, fume hood, cold room. - 🟦
No-load protection: Automatic shutdown if probe is in air. Saves tips and samples. - 🟦
20 protocol memory: Switch from E. coli lysis to nanoparticle mixing instantly. - 🟦
Temperature monitoring: Real-time °C shown on screen; optional cooling cell. - 🟦
Duty cycle 0.1–99.9%: Gentle on antibodies and temperature‑sensitive enzymes.
Validated applications
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In addition, cell biology: Mammalian, bacterial, yeast lysis – 30 s to 3 min. - ⚛️
Material science: Graphene, CNT, metal oxide dispersion (0.1–2% wt). - 💧
Formulation: Nanoemulsions, liposomes, cannabis oil emulsification. - 🍎
Food & cosmetic: Particle size reduction, stability testing. - 🌍
Environmental: Soil extraction, algae cell wall breaking.
Optimized ultrasonic settings for any sample type
PRACTICAL WORKFLOW – POWER & PULSE SETTINGS
How to get reproducible results (step‑by‑step)
1️⃣ Probe selection: Φ2 mm (0.1–5 mL), Φ3 mm (2–15 mL), Φ5 mm (10–150 mL), Φ6 mm (20–300 mL).
2️⃣ Amplitude check: Start at 30% duty cycle for delicate cells; 70–90% for hard tissues.
3️⃣ Pulse mode: Set ultrasound 3 s → gap 2 s → avoids thermal stress.
4️⃣ Depth control: Immerse probe 10–15 mm; never touch vessel bottom.
5️⃣ Memory save: Store successful runs (20 groups) – recall instantly.
🧪 COLO.Science quality commitment
Every USP‑400 is frequency‑swept and calibrated at our EU partner facility. We provide 12‑month warranty, 7‑year spare parts availability, and application protocols via email support.
🔧 Tip: Φ2, Φ3, Φ6 mm horns and flow‑cell attachments are in stock – ask for customisation.
| SKU / Model | Power output (adjustable) | Processing volume* | Standard horn | Ideal for | Typical applications |
|---|---|---|---|---|---|
| PRO5691 | 2.5 – 250 W | 0.1 – 150 mL | Φ5 mm titanium | Academic R&D, enzyme assays, DNA/RNA shearing, small-batch cell lysis | E. coli, yeast, mammalian cells; nanoparticle dispersion up to 50 mL |
| PRO5692 | 4 – 400 W | 0.1 – 300 mL | Φ5 mm titanium | Biotech scale‑up, tough tissues, high‑volume emulsification (100–300 mL) | Plant tissue, liposomes, cannabis oil, graphene, pilot batches |
* Processing volume depends on horn selection, sample viscosity and vessel geometry.
| Display | True‑color capacitive TFT touch screen, 4.3″ (adjustable brightness) |
|---|---|
| Single ultrasound time | 0.1 – 99.9 seconds (programmable) |
| Single gap (pause) time | 0.1 – 99.9 seconds |
| Total process timer | 1 second – 99 hours 59 minutes 59 seconds |
| Ultrasonic frequency | 20 – 30 kHz (automatic frequency tracking – AFT) |
| Temperature monitoring | 0 – 100 °C ±1 °C, real‑time display, compatible with optional cooling cell |
| Alarm & protection | Time, overload, no‑load, over‑temperature – audible and visual alerts |
| Duty cycle | 0.1 – 99.9 % (pulsed or continuous mode) |
| Program memory | 20 groups – store and recall complete protocols |
| Optional probes (horns) | Φ2 mm, Φ3 mm, Φ5 mm, Φ6 mm – titanium, autoclavable |
| Power supply | 110–120 V / 220–240 V, 50/60 Hz (universal input) |
| Dimensions (net) | 410 × 225 × 290 mm (D × W × H) |
| Weight | ~3.8 kg (handheld unit with cable) |
| Optional interfaces | Computer communication (RS‑232 / USB) + data printing |
Frequently asked questions – USP-400 homogenizer
❓ What is the difference between PRO5691 and PRO5692?
❓ Can I use USP-400 for DNA shearing?
❓ Which accessories are included in the box?
❓ Is there a cooling jacket or flow cell?
📩 Finally, have a different question? Email sales@colo.si – reply within 4h (CET).
⚡ EU stock / fast ship
🧪 Application support
